Department of Oral Biology

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Zambon, Joseph D.D.S, Ph.D. Professor, Department of Periodontics and Endodontics; Associate Dean for Academic Affairs, Office of Academic Affairs; Professor, Department of Oral Biology

Address:
222 Foster Hall
Buffalo, NY 14214
(716)829-2460
jjzambon@buffalo.edu

Faculty Profile

EDUCATION

B.S. (Biology), St. John Fisher College
D.D.S., University at Buffalo, School of Dental Medicine.
General Practice Residency, Navy Regional Medical Center, Portsmouth, VA.
Certificate in Periodontics, University at Buffalo, School of Dental Medicine.
Ph.D. (Oral Biology), University at Buffalo, School of Dental Medicine.

PRESENT POSITION:

Professor of Periodontology and Oral Biology, University at Buffalo, School of Dental Medicine.
Associate Dean for Academic Affairs, University at Buffalo, School of Dental Medicine.

AWARDS AND HONORS:

Fellow, International College of Dentists.
Lundquist Memorial Lectureship, Northwestern University.
Omicron Kappa Upsilon, National Dental Honor Society.
Tenenbaum Guest Lecturer, Columbia University.
R. Earl Robinson Periodontal Regeneration Award, American Academy of Periodontology.
Clinical Research Award, American Academy of Periodontology.
Richard A. Powell Award for Teaching Excellence.
Dental Educator of the Year, University at Buffalo, School of Dental Medicine.
Fellow, American College of Dentists.
Charles Lipani Award for Faculty Service.
University at Buffalo, Exceptional Scholar.


Research Profile

This laboratory focuses on clinical studies of oral bacteria and also on basic research on oral Gram-negative species. Clinical microbiological studies are performed; (1) in conjunction with clinical studies to characterize subject populations in determining the role of subgingival microorganisms as risk factors for periodontitis; (2) to evaluate the role of oral bacteria in oral manifestations of Acquired Immunodeficiency Syndrome; (3) in conjunction with clinical trials to examine the microbiological safety and efficacy of oral and periodontal therapy, and (4) serve as the basis for examining the distribution of virulence factors within and among oral bacterial species.







Basic research studies in the laboratory currently focus on the microbial genetics of Gram-negative periodontal pathogens such as Actinobacillus actinomycetemcomitans. Separate investigations are underway to examine (1) genetic diversity within species of bacterial pathogens; and (2) genetic regulation of bacterial virulence factors. These studies are funded by a combination of NIH grants and industrial support.

Representative Publications Search Publications in MEDLINE

RECENT PUBLICATIONS:

Haraszthy, V. I., Zambon, J. J., Trevisan, M., Zeid, M., Genco, R.J. 2000. Identification of periodontal pathogens in atheromatous plaques. J. Periodontol. 71:1554-1560.

Mastragelopulos, N., Haraszthy, V. I., Zambon, J. J., Zafiropoulos, G. G. 2001. Erste beweise einer interessanten bezielhung: paradontitis und gefaberkrankungen. Dental Hygiene Journal 2:34-37.

Noack, B., Genco, R. J., Trevesan, M., Grossi, S., Zambon, J. J., DeNardin, E., 2001 Periodontal infections contribute to elevated systemic C-reactive protein level. J. Periodontol. 72:1221-1227.

Haraszthy, V.I., Lally,, E. T., Haraszthy, G., Zambon, J. J. 2002. Molecular cloning of the fur gene from Actinobacillus actinomycetemcomitans. Infect Immun 70: 3170-9.

Mastragelopulos, N., Haraszthy, V. I., Zambon, J. J., Zafiropoulos, G. G. 2002. Nachweis parodontal pathogener mikroorganismen in atheromatosen plaques. Chirurg 73: 585-591.

Mastragelopulos, N., Rogge, S. Kielbassa, A. M., Haraszthy, V. I., Zambon, J. J., Brunkwall, J., Beaumont, C., and Zafiropoulos, G. G. K. 2004. Bakterielle Besidelung der atheromatosen plaques: parodontitis und arteriosklerose. Gefasschirugie 9: 332-338.

Cortelli, J. R., Cortelli, S. C., Jordan, J., Haraszthy, V. I., Zambon, J. J. 2005. Prevalence of periodontal pathogens in Brazilians with aggressive or chronic periodontitis. J. Clin. Periodontol 32: 860-86.

Haraszthy, V. I., Shawn F. Jordan, S. F.,1, and Joseph J. Zambon, J. J. 2005. Identification of Fur regulated genes in Actinobacillus actinomycetemcomitans. Microbiology 152:787-796.