School of Dental Medicine - University at Buffalo

Wang, Bing-Yan DMD, PhD Assistant Professor, Department of Periodontics and Endodontics; Assistant Professor, Department of Oral Biology

Address:

B22 Squire Hall

Buffalo, NY 14214

(716)829-3040

bwang@buffalo.edu

Research Profile

Focused on oral microbiology: Effect of oral bacteria interactions on quorum-sensing of Streptococcus mutans.

Representative Publications Search Publications in MEDLINE

1. Wang, B.Y., Ogasawara, K., Fukushi, N., Kajiwara, M., Onoe, K. Distribution and surface phenotype of intrathymic B lymphocytes determined by the thymic phenotype where B lymphocytes have developed. Allergy Immunol. (Life Science Adv.) 9:85-93, 1990
2. Arase, H., Fukushi, N., Wang, B.Y., Ogasawara, K., Good, R.A., Onoe, K. Specific and non-specific abolishment of self-tolerance acquired in the thymus. Clin. Immunol. 22:1080-1086, 1990
3. Wang, B. The laboratory examination of Candida albicans. Chinese J. Stomatology. 25:294-296, 1990
4. Fukushi, N., Arase, H., Wang, B.Y., Ogasawara, K., Gotohda, T., Good, R.A., Onoe, K. Thymus: a direct target tissue in graft-versus-host reaction after allogeneic bone marrow transplantation that results in abrogation of induction of self-tolerance. Proc. Natl. Acad. Sci. USA. 87:6301-6305, 1990
5. Fukushi, N., Wang, B.Y., Arase, H., Ogasawara, K., Good, R.A., Onoe, K. Cell components required for deletion of an autoreactive T cell repertoire. Eur. J. Immunol. 20:1153-1160, 1990
6. Hatakeyama, S., Ogasawara, K., Fukushi, N., Iwabuchi, C., Iwabuchi, K., Wang, B.Y., Kajiwara, M., Good, R.A., Onoe, K. Sequential analysis of distributions of donor-derived thymocytes bearing T-cell antigen receptor (TCR) and donor-derived Ia+ cells in thymuses of fully allogeneic bone marrow chimera in mice. Acta Pathol. Jpn. 40:391-401, 1990
7. Wang, B.Y. Histopathological analysis of 44 cases with oral candidiasis. Chinese J. Stomatology 26:333-335, 1991
8. Negishi, I., Ogasawara, K., Iwabuchi, K., Wang, B.Y., Good, R.A., Onoe, K. H-2K molecules positively select V¦Â 17a+ CD4- CD8+ T cells in bone marrow and thymic chimeras. Cell. Immunol. 136:185-193, 1991
9. Iwabuchi, C., Iwabuchi, K., Cobayashi, S., Ogasawara, K., Negishi, I., Wang, B.Y., Wambua. P.P., Arase, H., Fukushi, N., Itoh, Y., Good, R.A., Onoe, K. Deficiency in early development of the thymus-dependent cells in irradiation chimeras attributable to recipient's environment. J. Immunol. 146:26-34, 1991
10. Wang, B.Y., Itoh, Y., Gotohda, T., Ogasawara, K., Onoe, K. Vb chains of T cell antigen receptors on T cells reactive to a synthetic peptide antigen, p43-58. J. Clin. Exp. Med. 156:497-498, 1991
11. Kizaki, T., Ishige, M., Kobayashi, S., Wang, B., Kumagai, M., Day, N.K., Good, R.A., One, K. Suppression of T-cell Proliferation by CD8+ T cells induced in the presence of Protoscoleces of Echinococcus multilocularis in vitro. Infect. Immunol. 61:525-533, 1993
12. Kizaki, T., Ishige, M., Wang, B., Day, N.K., Good, R.A., Onoe, K. Generation of CD8+ suppressor T cells by protoscoleces of Echinococcus multilocularis in vitro. Immunol. 79:412-417, 1993
13. Kizaki, T., Ishige, M., Wang, B., Kumagai, M., Day, N.K., Good, R.A., Onoe, K. Interleukin-1-dependent mitogenic responses induced by protoscoleces of Echinococcus multilocularis in murine lymphocytes. J. Leukocyte Biol. 53:233-239, 1993
14. Wang, B. Characteristics of intrathymic B cells in normal and chimera mice. Hokkaido J. Med. Sci. 68:496-506, 1993
15. Arase-Fukushi, N., Arase, H., Wang, B., Hirano, M., Ogasawara, K., Good, R.A., Onoe, K. Influence of a small number of mature T cells in donor bone marrow inocula on lymphoid tissues and negative selection of a T cell repertoire in the recipient. Microbiol. Immunol. 37:883-894, 1993
16. Wang, B., Onoe, K., and Good, R.A. Mature CD4+ cells help lineage negative but not more purified, MHC class I bright marrow cells to cross MHC transplantation barrier. Bone Marrow Transplantation: Foundations for the 21st Century p379, 1996
17. Wang, B. and Good, RA. Highly purified hematopoietic stem cells can repopulate congeneic recipients in mice. Allergy & Clinical Immunology. 99:S273; 1997
18. Wang BY. Cherry. El-Badri NS. Good RA. Prevention of development of autoimmune disease in BXSB mice by mixed bone marrow transplantation. Proc. Natl. Acad. Sci. USA. 94(22):12065-12069, 1997
19. Wang, B.Y., El-Badri, N.S., Cherry and Good, R.A.: Purified hematopoietic stem cells alone, without facilitating cells, can repopulate fully allogeneic recipients across entire transplantation barrier. Proc. Natl. Acad. Sci. USA. 94:14632-14636, 1997
20. Uckan D. Steele A. Cherry. Wang BY. Chamizo W. Koutsonikolis A. Gilbert-Barness E. Good RA. Trophoblasts express Fas ligand: a proposed mechanism for immune privilege in placenta and maternal invasion. Molecular Human Reproduction. 3(8):655-662, 1997
21. El-Badri, N.S., Wang, B., Cherry and Good, R.A.: Osteoblasts promote engraftment of allogeneic hematopoietic stem cells. Exp. Hematol. 26:110-116, 1998
22. Cherry, Engelman, R.W., Wang, B.Y., Kinjoh, K., El-Badri, N.S., Good, R.A.: Calorie restriction delays the crescentic glomerulonephritis of SCG/Kj mice. Proc. Soc. Exp. Bio. Med. 218:218-222, 1998
23. Cherry, Engelman, R.W., Wang, B.Y., Kinjoh, K., El-Badri, N.S., Good, R.A.: Prevention of crescentic glomerulonephritis in SCG/Kj mice by bone marrow transplantation. Proc. Soc. Exp. Bio. Med. 218:223-228, 1998
24. Wang B. Yamamoto Y. El-Badri NS. Good RA. Effective treatment of autoimmune disease and progressive renal disease by mixed bone-marrow transplantation that establishes a stable mixed chimerism in BXSB recipient mice. Proc. Natl. Acad. Sci. USA. 96(6):3012-3016, 1999
25. El-Badri NS. Wang BY. Steele A. Cherry. Marikar Y. Mizobe K. Good RA. Successful prevention of autoimmune disease by transplantation of adequate number of fully allogeneic hematopoietic stem cells. Transplantation. 70(6):870-877, 2000
26. Scannapieco FA. Wang B. Shiau HJ. Oral bacteria and respiratory infection: effects on respiratory pathogen adhesion and epithelial cell proinflammatory cytokine production. Ann Periodontol 6:78-86, 2001
27. Wang BY. Chi B. Kuramitzu HK. Genetic Exchange between Treponema denticola and Streptococcus gordonii in biofilms. Oral Microbiol. Immunol. 17:108-112, 2002
28. Yamamoto Y. Wang B. Fukuhara S. Ikehara S. Good RA. Mixed peripheral blood stem cell transplantation for autoimmune disease in BXSB/MpJ mice. Blood. 100(5):1886-93, 2002
29. Good RA. Wang BY. El-Badri NS. Steele A. Verjee T. Mixed Bone Marrow or Mixed Stem Cell Transplantation for Prevention or Treatment of Lupus-Like Diseases in Mice. Experimental Nephrology. 10:408-420, 2002
30. Wang BY. Kuramitsu HK. Interactions between oral biofilm bacteria: Streptococcus gordonii inhibition of Streptococcus mutans bacteriocin production. Applied Environmental Microbiology. 71:354-362, 2005
31. Kuramitsu HK. Wang BY. Virulence properties of cariogenic bacteria. BMC Oral Health. 15:6 Suppl 1:S11, 2006
32. Xie H. Lin X. Wang BY. Wu J. Lamont RJ. Identification of a signaling molecule involved in bacterial intergeneric communication. Microbiology. Microbiology. 2007 Oct;153(Pt 10):3228-34.