Bone and Connective Tissues/Tissue Engineering SHUYING (SHERI) YANG, MD, PhD personal profile
Mechanism of bone resorpton and bone formation; gene therapy and stem cell mediated periodontal and craniofacial bone regeneration
Note: Another area of our research is available at Immunology and Innate Defenses
Most adult skeletal diseases are due to excess osteoclastic activity, leading to an imbalance in bone remodeling which favors resorption. Such diseases would include osteoporosis, periodontal disease, rheumatoid arthritis, multiple myeloma and metastatic cancers. Therefore, understanding the molecular mechanisms of osteoclast and osteoblast differentiation and activation is critical for successful treatment of these diseases. My current research efforts focus on identifying the role and mechanism of novel or known genes in bone-related signal pathways and understanding how these genes regulate bone formation and bone resorption by using gene knockout technology. We are also working on gene therapy and stem cell mediated periodontal and craniofacial bone regeneration.
“Every student has a primary mentor and a committee who guide the student throughout the five or six years of study that it takes.”